D-TYROSINOL HYDROCHLORIDE |
PRODUCT
IDENTIFICATION
|
CAS
NO. |
40829-04-7 |
|
EINECS
NO. |
|
FORMULA |
C9H13NO2·HCl |
MOL
WT. |
203.67 |
H.S.
CODE
|
|
TOXICITY
|
|
SYNONYMS |
[(R)-3-(4-Hydroxyphenyl)-2-amino-1-propanol] Hydrochloride;
|
(R)-beta-Amino-4-hydroxybenzenepropanol hydrochloride;
|
DERIVATION
|
|
CLASSIFICATION
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
PHYSICAL
STATE |
white
crystalline powder
|
MELTING
POINT |
161
- 165 C (Decomposes) |
BOILING
POINT |
|
SPECIFIC
GRAVITY |
|
SOLUBILITY
IN WATER |
Soluble |
pH |
|
VAPOR
DENSITY |
|
AUTOIGNITION
|
|
NFPA
RATINGS
|
|
REFRACTIVE
INDEX
|
|
FLASH
POINT |
|
STABILITY |
Stable
under ordinary conditions. |
GENERAL
DESCRIPTION
|
Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc)
are versatile building blocks, auxiliaries, ligand or resolving
agent in asymmetric synthesis for biological research and pharmaceutical
applications such as antitumor, anesthetic, antipasmodic, hepatotoxic,
antiinflammatory or anti-HIV activities. They are used in the synthesis of
beta-blockers, HIV protease and ACE inhibitors, chiral auxiliaries and catalytic
enantioselective ligands. Their derivatives include the forms of;
- C-terminal peptibiols
- Amphiphylic antibacterial
peptides
- Oligocarbamates
- Analogs of peptides
- Aziridines, Halogen
aminoalkyls
- Enantiomerical alpha-alkyl mono and diamines
- Enantiomerical
beta-substituted amines
- Enantiomerical beta-amino acids beta-amino
sulfoxides, beta-amino sulfides and beta-amino thiols.
- The precursors of
diverse compounds such as statines, sphingolipides and peptide isosteres.
(R,R)-(-)-2,4-Pentanediol
is an
effective diol for asymmetric chiral applications such
as
chiral auxiliaries, building blocks, chiral
ligands. |
SALES
SPECIFICATION |
APPEARANCE
|
white
crystalline powder
|
CHEMICAL
PURITY
|
98.5%
min (G.C) |
ENANTIOMERIC EXCESS |
99.0%
min (G.C) |
TRANSPORTATION |
PACKING |
|
HAZARD
CLASS |
8
(Packing Group: II) |
UN
NO. |
2735 |
OTHER
INFORMATION |
Hazard Symbols: XI, Risk Phrases: 3637/38,
Safety Phrases: 26-37/39 Optical
Rotation: +17° ~ +19° (C=1 in water) |
|